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The England captain has been sidelined with a rib injury and last played against Bayer Leverkusen on November 13.
Rio Ferdinand is still out with a thigh injury but could be back for Saturday`s Premiership showdown with bottom club West Ham.
Sir Alex Ferguson has hinted he is likely to stick with the starting line-up which beat Arsenal on Saturday, even though Beckham is available again.
Leading scorer Ruud van Nistelrooy is likely to start as a lone striker with Ole Gunnar Solskjaer making up a five-man midfield. At the other end, pace could be the key for United.
Roy Makaay has already scored eight goals in the Champions League this season and offers plenty of speed up front for Deportivo. As a result, Ferguson is expected to stick with the centre-half combination of Wes Brown and Mikael Silvestre that coped with the pace of Thierry Henry and Sylvain Wiltord against Arsenal on Saturday.
Phil Neville will continue in central midfield following a man-of-the-match performance against the Gunners, and he will once again have a tough job on his hands against one of the most creative midfields in Spain.
Deportivo see midfielder Juan Carlos Valeron return from the broken leg he sustained in the first round of the competition in September. He was brought on for a short spell during Saturday's 1-1 draw at Recreativo Huelva and came through with no problems.
The Spaniard's creativity has been sorely missed by Deportivo, and his comeback coincides with the returns of midfielder Sergio and full-back Enrique Romero, who were both rested at the weekend.
One bright spot for United fans is the news that Argentine midfielder Aldo Duscher has been left out of the squad by coach Javier Irureta.
Duscher, the man responsible for inflicting the foot injury that nearly kept David Beckham out of the World Cup last season, said: "It is a shame to miss such a big game.
"I would have liked to have talked with him and swappped shirts after the game."
Manchester United (probable): 1-Fabien Barthez; 2-Gary Neville, 24-Wes Brown, 27-Mikael Silvestre, 22-John O'Shea; 3-Phil Neville, 4-Juan Sebastian Veron, 11-Ryan Giggs, 18-Paul Scholes, 20-Ole Gunnar Solskjaer; 10-Ruud van Nistelrooy.
Deportivo Coruna (probable): 25-Juanmi; 12-Lionel Scaloni, 5-Cesar, 20-Donato, 3-Enrique Romero; 6-Mauro Silva, 16-Sergio, 10-Fran, 21-Juan Carlos Valeron; 7-Roy Makaay, 9-Diego Tristan.
Referee: Terje Hauge (Norway).
I think it will be a tight game but Man u will nick all the points.
What do you lot think?
The England captain has been sidelined with a rib injury and last played against Bayer Leverkusen on November 13.
Rio Ferdinand is still out with a thigh injury but could be back for Saturday`s Premiership showdown with bottom club West Ham.
Sir Alex Ferguson has hinted he is likely to stick with the starting line-up which beat Arsenal on Saturday, even though Beckham is available again.
Leading scorer Ruud van Nistelrooy is likely to start as a lone striker with Ole Gunnar Solskjaer making up a five-man midfield. At the other end, pace could be the key for United.
Roy Makaay has already scored eight goals in the Champions League this season and offers plenty of speed up front for Deportivo. As a result, Ferguson is expected to stick with the centre-half combination of Wes Brown and Mikael Silvestre that coped with the pace of Thierry Henry and Sylvain Wiltord against Arsenal on Saturday.
Phil Neville will continue in central midfield following a man-of-the-match performance against the Gunners, and he will once again have a tough job on his hands against one of the most creative midfields in Spain.
Deportivo see midfielder Juan Carlos Valeron return from the broken leg he sustained in the first round of the competition in September. He was brought on for a short spell during Saturday's 1-1 draw at Recreativo Huelva and came through with no problems.
The Spaniard's creativity has been sorely missed by Deportivo, and his comeback coincides with the returns of midfielder Sergio and full-back Enrique Romero, who were both rested at the weekend.
One bright spot for United fans is the news that Argentine midfielder Aldo Duscher has been left out of the squad by coach Javier Irureta.
Duscher, the man responsible for inflicting the foot injury that nearly kept David Beckham out of the World Cup last season, said: "It is a shame to miss such a big game.
"I would have liked to have talked with him and swappped shirts after the game."
Manchester United (probable): 1-Fabien Barthez; 2-Gary Neville, 24-Wes Brown, 27-Mikael Silvestre, 22-John O'Shea; 3-Phil Neville, 4-Juan Sebastian Veron, 11-Ryan Giggs, 18-Paul Scholes, 20-Ole Gunnar Solskjaer; 10-Ruud van Nistelrooy.
Deportivo Coruna (probable): 25-Juanmi; 12-Lionel Scaloni, 5-Cesar, 20-Donato, 3-Enrique Romero; 6-Mauro Silva, 16-Sergio, 10-Fran, 21-Juan Carlos Valeron; 7-Roy Makaay, 9-Diego Tristan.
Referee: Terje Hauge (Norway).
I think it will be a tight game but Man u will nick all the points.
What do you lot think?
Phil Neville seems to have found a new vocation in life by actually playing well at football, so it will be interesting to see if/how he plays.
Personally, I expect we'll win it though. We'll want to try to make it hard for them to qualify, so we don't have tpo run into them again.
Man U are also on good form, which should help things a lot too.
Deportivo are one of my favourite European clubs, and one of the teams that I really enjoy watching, but to be honest, I can't see them beating Man U tonight - maybe, just maybe, they can take a draw away from Old Trafford, but I'd put money on Man U winning this one.
The downside for Man U is, all the Spanish teams seem to be playing really well in the Champions League, and just not in their own league. For example:
3rd - Valencia
6th - Real Madrid
8th - Deportivo
12th - Barcelona
That's the situation in La Liga, but all teams, although not doing well at home, are all on great form in Europe.
As I said before, Deportivo are a good team, but I don't think Man U should have too much bother tonight.
Ruud van Nistelrooy with both goals.
Van Nistelrooy could have had 6.
Bad reffereeing!!
I wouldn't say that van Nistelrooy deserved that first penalty claim, or Giggs' one where he went down, but I'm still left convinced that a spot-kick should've been awarded when Ruud went down the second time!
And why was Veron booked??
Did van Nistelrooy even touch the 'keeper when he headed in that goal that should've been his second?? No!
At least we got all 3 points, though. And thanks to Barthez, we didn't concede. O'Shea always seems to impress me every-time I see him play now!
That should put us in a very comfortable position for when it all picks-up again in February.