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It wasn't unbearable though, just happened at certain times.
My guess is it's ya modded 'Box.
Considered looking at the screen aspect ratios in the dashboard, if you still have one? I don't know why it would cause problems but perhaps if it is set at widescreen or something it could interfere.
Last thought is that there was a big patch/content thing for Ninja Gaiden on Live that made it run faster and added a time trial mode or something. In the unlikely event you have that then get it.
(Guess i should've posted about Halo 2 or some equally boring thread thats been done to death a million times. Cheers for your help everyone!)