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As for the shrine, try looking for it with the TES map utility - [URL]http://broncosmvp.tripod.com/Utilities.htm[/URL]
Sunder and keening dont kill you instantly.... it's only about 90 health per second of damage they do. So you need to be under the effect of at least five exclusive restore health potitions at the same time for as long as it takes you to kill the heart.